Validation of impaired Transient Receptor Potential Melastatin 3 ion channel activity in natural killer cells from Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis patients.

Syndrome of chronic fatigue / myalgic encephalomyelitis (CFS / ME) is a complex multifactorial disease of unknown cause with multi-system events. Although the etiology of CFS / ME remains elusive, immunological dysfunction and specifically low cytotoxic activity in natural killer (NK) cells is the result of more consistent laboratory. The transient receptor potential (TRP) superfamily … Read more

Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test.

Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test.

The mitochondrial energy score (TSS) protocol developed by the group Myhill, is marketed as a diagnostic test for chronic fatigue syndrome / myalgic encephalomyelitis (CFS / ME). This study evaluated the reliability and reproducibility of the test, currently provided by private clinics, to assess its potential to be developed as an NHS accredited laboratory test. … Read more

Modification of Immunological Parameters, Oxidative Stress Markers, Mood Symptoms, and Well-Being Status in CFS Patients after Probiotic Intake: Observations from a Pilot Study.

Modification of Immunological Parameters, Oxidative Stress Markers, Mood Symptoms, and Well-Being Status in CFS Patients after Probiotic Intake: Observations from a Pilot Study.

The present study discusses the effects of a combination of probiotics can stimulate the immune system of patients with chronic fatigue syndrome / myalgic encephalomyelitis (CFS / ME). For this purpose, patients diagnosed according to the criteria of Fukuda and treated with probiotics were analyzed by clinical and laboratory evaluations, before and after probiotic administration. … Read more